Actually if you got a guy full of angst walking around hardly ever running into someone while talking to himself it would seem kinda weird imho. Hence I like Blame the way it is.
Arrgh not biomega! Well if biomega is anything along the line of blame! as far as dialogue (or the distinct lack of dialogue) goes, there shouldn't be much translating to do. Of course you don't have to translate the japanese fx. Just make a little note on the bottom of the panel that says "Bla...